Intrauterine Insemination (IUI)

Achieving Your Fertility Goals

At Northeastern Reproductive Medicine, our goal is to maximize your chances of success based on your age and the results of diagnostic testing.

IUI is one of the primary fertility treatments we offer, designed to increase the likelihood of sperm meeting the egg. This minimally invasive procedure can be an excellent first step for many couples and individuals experiencing fertility challenges. Our experienced team ensures that each IUI cycle is carefully timed and personalized to optimize your chances of conception.

What is IUI?

The IUI procedure is a basic reproductive technique that deposits washed sperm into the uterus at the time of ovulation. The sperm source can be fresh or frozen, from a partner or a donor. The goal is for the sperm to swim into the fallopian tube and fertilize a waiting egg, resulting in a pregnancy. IUI can be coordinated with your normal cycle or with fertility medications.

Interested in IUI?

NRM is ready to support you every step of the way.

Schedule a consultation

Fertility Medications: What Medications May be Used?

There are two oral medications that are most commonly used: clomiphene (Clomid®) and letrozole (Femara®).

Oral medications are taken at the beginning of the woman’s cycle, starting between day 3 and 5 of the cycle and continuing for 5 days.

A transvaginal ultrasound will be performed, usually around cycle days 10-12, to evaluate follicular response to the medication. Ideally, only one follicle will have responded to the medication. Some women may have two or more follicles, which could result in a multiple pregnancy.

Your physician may prescribe an injectable medication called human chorionic gonadotropin (HCG) to be given at a specified time to induce ovulation, about 40 hours before the IUI. This medication will cause the egg to leave the follicle and start moving down the fallopian tube.

For other patients, injectable medications may be prescribed to stimulate the ovaries. Gonadotropins such as Menopur®, Bravelle®, Gonal-F®, or Follistim® will be prescribed by your doctor and you will be closely monitored by ultrasound for follicle development. Some women develop multiple follicles with gonadotropin therapy and risks of this therapy include multiple pregnancy.